Ja. Shields et al., SURGICAL-MANAGEMENT OF CIRCUMSCRIBED CONJUNCTIVAL MELANOMAS, Ophthalmic plastic and reconstructive surgery, 14(3), 1998, pp. 208-215
Circumscribed conjunctival melanoma usually arises in the bulbar conju
nctiva and less often in the forniceal or palpebral conjunctiva. After
simple superficial removal, employed by many ophthalmologists, these
tumors have an increased tendency toward local recurrence and distant
metastasis. A surgical procedure designed to remove the tumors complet
ely and minimize the chances of recurrence would be desirable. The aut
hors employed a surgical approach to conjunctival melanoma excision, w
hich they believe insures more complete tumor removal and decreases th
e chances of recurrence and metastasis. The surgical management of mel
anoma in the limbal region of the bulbar conjunctiva consists of local
ized alcohol epitheliectomy, removal of the mass by a partial lamellar
scleroconjunctivectomy, and supplemental double freeze-thaw cryothera
py to the adjacent remaining conjunctiva by a specific technique. For
tumors located in the forniceal or palpebral conjunctiva, wide surgica
l resection with alcohol treatment to the scleral base and cryotherapy
to the surrounding conjunctiva is performed. A ''no touch'' technique
is employed and direct manipulation of the tumor is strictly avoided
in an effort to prevent tumor cell seeding into a new area. The techni
que currently employed has evolved from experience with circumscribed
conjunctival melanoma excision during a 20-year period. About 80 patie
nts had circumscribed conjunctival melanoma unassociated with apprecia
ble primary acquired melanosis. Although it is not the purpose of this
article on surgical technique to provided a detailed statistical anal
ysis of the results, the authors currently believe that this technique
should be employed in all cases of circumscribed lesions in which con
junctival melanoma is a diagnostic consideration. Incisional biopsy an
d frozen sections are generally not advisable. Preliminary observation
s suggest that this method decreases the chances of local recurrence.