STEREOSELECTIVE MICHAEL ALDOL TANDEM REACTION TRIGGERED BY THIOLATE ANION OR ANALOGS/

Authors
KAMIMURA A MITSUDERA H ASANO S KAKEHI A NOGUCHI M
Citation
A. Kamimura et al., STEREOSELECTIVE MICHAEL ALDOL TANDEM REACTION TRIGGERED BY THIOLATE ANION OR ANALOGS/, Chemical communications, (10), 1998, pp. 1095-1096
Citations number
24
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
10
Year of publication
1998
Pages
1095 - 1096
Database
ISI
SICI code
1359-7345(1998):10<1095:SMATRT>2.0.ZU;2-M
Abstract
A combination of a tert-butyl alpha,beta-unsaturated ester, an aldehyd e and lithium thiophenolate in CH2Cl2 undergoes a one-pot Michael/aldo l tandem reaction to give a condensation adduct of the three component s, an alpha-phenylthiomethyl-beta-hydroxy ester, in good yield with hi gh syn-selectivity.