AN EFFICIENT CHEMICAL METHOD FOR REMOVING N-TERMINAL EXTRA METHIONINEFROM RECOMBINANT METHIONYLATED HUMAN GROWTH-HORMONE

Authors
NISHIMURA O SUENAGA M OHMAE H TSUJI S FUJINO M
Citation
O. Nishimura et al., AN EFFICIENT CHEMICAL METHOD FOR REMOVING N-TERMINAL EXTRA METHIONINEFROM RECOMBINANT METHIONYLATED HUMAN GROWTH-HORMONE, Chemical communications, (10), 1998, pp. 1135-1136
Citations number
16
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
10
Year of publication
1998
Pages
1135 - 1136
Database
ISI
SICI code
1359-7345(1998):10<1135:AECMFR>2.0.ZU;2-7
Abstract
Conversion of recombinant methionylated human growth hormone (Met-hGH) into its non-methionylated form (hGH) has been successfully achieved by a chemical process, which consists of a transamination reaction and phenylene-1,2-diamine treatment.