NEW PROCEDURES FOR THE JULIA-COLONNA ASYMMETRIC EPOXIDATION - SYNTHESIS OF (-CLAUSENAMIDE())

Authors
CAPPI MW CHEN WP FLOOD RW LIAO YW ROBERTS SM SKIDMORE J SMITH JA WILLIAMSON NM
Citation
Mw. Cappi et al., NEW PROCEDURES FOR THE JULIA-COLONNA ASYMMETRIC EPOXIDATION - SYNTHESIS OF (-CLAUSENAMIDE()), Chemical communications, (10), 1998, pp. 1159-1160
Citations number
22
Categorie Soggetti
Chemistry
Journal title
Chemical communications → ACNP
ISSN journal
13597345
Issue
10
Year of publication
1998
Pages
1159 - 1160
Database
ISI
SICI code
1359-7345(1998):10<1159:NPFTJA>2.0.ZU;2-B
Abstract
The oxidation of chalcone 1 to optically active epoxide 2 [a precursor of (+)-clausenamide (+)-3] may be effected using a 15-mer or 20-mer o f L-leucine bound to a PEG based support; poly-L-leucines of this type may be used as immobilised catalysts in a fixed-bed reactor.