HOME VACCINATION FOR CHILDREN BEHIND IN THEIR IMMUNIZATION SCHEDULE -A RANDOMIZED CONTROLLED TRIAL

Objective: To ascertain the effectiveness of a home vaccination servic e for children behind in their vaccination schedule. Design: Randomise d controlled trial of nurse-administered vaccination at home. Children were allocated at random to the intervention or the control group bef ore any contact with the parents was made. Setting: 10 council areas i n north-west metropolitan Melbourne defined by 56 postcode zones. Six- week intervention period from November 1996. Participants: 405 childre n - all those in the study area (n=2610) 90 days late (age 9 months) f or their third theria-tetanus-pertussis/poliomyelitis/Haemophilus infl uenzae type B (DTP/OPV/Hib) vaccination, or 120 days late (age 16 mont hs) for their measles-mumps-rubella (MMR) vaccination, according to th e Australian Childhood Immunisation Register. Main outcome measures: N umber of children completing DTP/OPV/Hib or MMR during the interventio n period, and number up to date before intervention. Results: Verifica tion of vaccination status with the parents revealed that 123 (60%) of the children in the intervention group and 113 (56%) of those in the control group were up to date with their vaccinations, leaving a study population of 81 (intervention group) and 88 (control group). Vaccina tion was achieved in 46 (57%) intervention children and 24 (27%) contr ol children (risk ratio [RR], 2.08; 95% CI, 1.4-3.1; P< 0.001). For DT P/OPV/Hib, 18/32 (56%) intervention children and 12/36 (33%) control c hildren were vaccinated (P= 0.06). For MMR, 28/49 (57%) and 12/52 (23% ) children were vaccinated, respectively (P<0.001). Home vaccinations were completed with 26 families (including five siblings). The average cost per child vaccinated as a result of the home program was $92.52. Conclusion: Home vaccination for children behind in their immunisatio n schedule is an effective, acceptable and relatively cheap method of completing recommended vaccinations. We recommend that a home vaccinat ion program be widely implemented and made available, particularly for disadvantaged families.