The composition of atherosclerotic plaques in the carotid artery is as
sumed to be related to the development of neurological symptoms. The e
cho patterns produced by B-mode ultrasound may be of use in the assess
ment of the plaques' composition. It is suggested that fibrotic and ''
stable'' plaques are more echogenic than lipid/hemorrhagic and echoluc
ent or ''unstable'' plaques. B-mode ultrasound procedures were perform
ed 1 day prior to surgery on 46 consecutive endarterectomies, Two obse
rvers assessed the plaques according to their echo pattern and echogen
icity and sorted them into three categories: 1) predominantly echoluce
nt, 2) heterogeneous, and 3) predominantly echogenic, The intraobserve
r agreement was moderate (kappa = 0.44) and the interobserver agreemen
t low (kappa = 0.38), Furthermore, subjective categorization of plaque
types resulted in type 1 plaques being as fibrotic as type 2 or 3 pla
ques. We conclude that B-mode ultrasound and subsequent subjective cat
egorization of atherosclerotic plaques cannot adequately determine the
volume of fibrosis or lipids within the plaque. (C) 1998 World Federa
tion for Ultrasound in Medicine & Biology.