DEPRESSION AND SHORT REM LATENCY IN SUBJECTS WITH CHRONIC-FATIGUE-SYNDROME

Objective: The hypothesized polysomnographic marker for depression, Ra pid Eye Movement Latency (REML), was used to investigate two groups of subjects; Chronic Fatigue Syndrome (CFS)-not depressed and CFS-depres sed. Method: CFS subjects were classified into depressed and not depre ssed groups, using the Diagnostic Interview Schedule (DIS), and subseq uently were studied in a sleep laboratory to ascertain REML. Results: Short REML showed a statistically significant correlation with the dep ressed state in CFS subjects. Conclusion: Short REM latency is associa ted with depression in the CFS population.