Renal medullary carcinoma has recently been described as an aggressive
neoplasm affecting young African Americans with sickle cell disease o
r sickle cell trait. We report the presentation, treatment, and outcom
e in 3 patients with renal medullary carcinoma along with a descriptio
n of the unsuccessful treatment attempts. A brief discussion and revie
w of the literature is included. (C) 1998, Elsevier Science Inc. All r
ights reserved.