MEASUREMENT OF CHEMICAL-SHIFTS AND COUPLING-CONSTANTS FOR GLUTAMATE AND GLUTAMINE

Authors
GOVINDARAJU V BASUS VJ MATSON GB MAUDSLEY AA
Citation
V. Govindaraju et al., MEASUREMENT OF CHEMICAL-SHIFTS AND COUPLING-CONSTANTS FOR GLUTAMATE AND GLUTAMINE, Magnetic resonance in medicine, 39(6), 1998, pp. 1011-1013
Citations number
14
Categorie Soggetti
Radiology,Nuclear Medicine & Medical Imaging
Journal title
Magnetic resonance in medicine → ACNP
ISSN journal
07403194
Volume
39
Issue
6
Year of publication
1998
Pages
1011 - 1013
Database
ISI
SICI code
0740-3194(1998)39:6<1011:MOCACF>2.0.ZU;2-I
Abstract
Proton chemical shifts and coupling constants were obtained for glutam ate and glutamine in water (D2O) at pH = 6.6. Initial chemical shift a nd coupling constant values obtained from experimental spectra were re fined using a spectral simulation and optimization program to get a co mplete set of values that could not otherwise be measured directly fro m the experimental spectra due to strong spin-spin couplings. These va lues are essential for automated spectral fitting procedures that requ ire a priori information.