THE NORMAL PLACENTA - IMMUNE ANATOMY AND FUNCTION

Authors
SALAFIA CM
Citation
Cm. Salafia, THE NORMAL PLACENTA - IMMUNE ANATOMY AND FUNCTION, Immunology and allergy clinics of North America, 18(2), 1998, pp. 271
Citations number
89
Categorie Soggetti
Allergy,Immunology
Journal title
Immunology and allergy clinics of North America → ACNP
ISSN journal
08898561
Volume
18
Issue
2
Year of publication
1998
Database
ISI
SICI code
0889-8561(1998)18:2<271:TNP-IA>2.0.ZU;2-P
Abstract
The placenta serves as both a barrier and a transporter at the materna l-fetal interface. Failure of either function leads to fetal compromis e. Normal placental function requires appropriate early maternal-place ntal immune interaction in the implantation site; normal uteroplacenta l perfusion; careful regulation of coagulation pathways; and a healthy villus trophoblast, stroma, and vasculature. This article discusses b asic underlying principles.