SOLID-PHASE SYNTHESIS OF GUANIDINES

Authors
ROBINSON S ROSKAMP EJ
Citation
S. Robinson et Ej. Roskamp, SOLID-PHASE SYNTHESIS OF GUANIDINES, Tetrahedron, 53(19), 1997, pp. 6697-6705
Citations number
19
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
19
Year of publication
1997
Pages
6697 - 6705
Database
ISI
SICI code
0040-4020(1997)53:19<6697:SSOG>2.0.ZU;2-S
Abstract
A comparison of guanylating agents 1 and 2 was performed on a series o f primary, secondary and aromatic amines in solution and on solid phas e resins. Thiourea 1 performed well in solution and on solid supported primary and secondary amines. Pyrazole 2 performed well in each case, except one aniline which failed to react. (C) 1997 Published by Elsev ier Science Ltd.