The association between sex hormones and chronic headache has been the
subject of a good deal of speculation. Headache is predicted to impro
ve during pregnancy, when estrogen levels rise steadily until delivery
. Retrospective studies have suggested that women with a history of mi
graines do tend to report decreases in headache activity with pregnanc
y. The purpose of this naturalistic study was to examine changes in he
adache that may occur during pregnancy and postpartum in women complai
ning of migraine, tension-type, or combined migraine and tension-type
headaches in a prospective design. Thirty women recorded their headach
es daily throughout pregnancy and up to 12 weeks postpartum. Results b
ased on these ratings demonstrated a nonsignificant trend for headache
to decrease throughout pregnancy and to increase during the birth wea
k. Headache patterns varied slightly depending on headache diagnosis a
nd parity. Contrary to previous retrospective study reports, migraine
sufferers demonstrated an increase in headache in the third trimester.
In addition, there was a tendency in multiparous woman for headaches
to increase in the third trimester, whereas primiparous women reported
less headache activity throughout pregnancy and the postpartum.