ANTIPROLIFERATIVE CONSTITUENTS IN UMBELLIFERAE PLANTS - IV - CONSTITUENTS IN THE FRUITS OF ANTHRISCUS-SYLVESTRIS HOFFM

Authors
IKEDA R NAGAO T OKABE H NAKANO Y MATSUNAGA H KATANO M MORI M
Citation
R. Ikeda et al., ANTIPROLIFERATIVE CONSTITUENTS IN UMBELLIFERAE PLANTS - IV - CONSTITUENTS IN THE FRUITS OF ANTHRISCUS-SYLVESTRIS HOFFM, Chemical and Pharmaceutical Bulletin, 46(5), 1998, pp. 875-878
Citations number
6
Categorie Soggetti
Chemistry Medicinal",Chemistry,"Pharmacology & Pharmacy
Journal title
Chemical and Pharmaceutical Bulletin → ACNP
ISSN journal
00092363
Volume
46
Issue
5
Year of publication
1998
Pages
875 - 878
Database
ISI
SICI code
0009-2363(1998)46:5<875:ACIUP->2.0.ZU;2-A
Abstract
The constituents in the fruit of Anthriscus sylvestris HOFFM, were inv estigated, and four lignans [deoxypodophyllotoxin, morelensin, (-)-deo xypodorhizorne, and (-)-hinokinin], one phenylpropanoid 1-(3',4'-dimet hoxyphenyl)-1-xi-hydroxy-2-propene], two phenylpropanoid esters [3',4' -dimethoxycinnamyl (Z)-2-angeloyloxymethyl-2-butenoate and 3',4'-dimet hoxycinnamyl (Z)-2-tigloyloxymethyl-2-butenoate], and one polyacetylen ic compound (falcarindiol) were isolated. Their antiproliferative acti vity against MK-1, HeLa and B16F10 cell lines is reported.