E. Cicinelli et al., TOPICAL ANESTHESIA FOR HYSTEROSCOPY IN POSTMENOPAUSAL WOMEN, The Journal of the American Association of Gynecologic Laparoscopists, 4(1), 1996, pp. 9-12
Study Objective. To evaluate the efficacy and safety of topical anesth
esia in reducing pain and the frequency of vasovagal reactions during
diagnostic hysteroscopy with endometrial biopsy in postmenopausal wome
n. Design. Randomized, placebo-controlled, double-blind study. Setting
. A university hospital. Patients. Forty-two postmenopausal women unde
rgoing diagnostic hysteroscopy and endometrial biopsy. Interventions.
Two milliliters of 2% mepivacaine or saline solution was injected tran
scervically into the uterine cavity before performing the procedures.
Measurements and Main Results. Pain was evaluated on a visual analog s
cale, and heart rate and blood pressure were monitored continuously. A
nesthesia reduced the pain experienced at hysteroscopy and endometrial
biopsy, but not significantly The frequency of vasovagal reactions wa
s significantly lower in the anesthetized group. Conclusions. Topical
anesthesia effectively prevents the occurrence of vasovagal reactions
in postmenopausal women undergoing hysteroscopy and endometrial biopsy
.