H. Danner et al., BACILLUS-STEAROTHERMOPHILUS FOR THERMOPHILIC PRODUCTION OF L-LACTIC ACID, Applied biochemistry and biotechnology, 70-2, 1998, pp. 895-903
A process for the continuous production of high purity L-lactic acid i
n a membrane bioreactor at 65 degrees C has been developed. Two differ
ent Bacillus stearothermophilus strains have been tested in batch expe
riments. Lactic acid yields are between 60 and more than 95% of theore
tical yields. The amounts of ethanol, acetate, and formate formed vari
ed between 0 and 0.4, 0 and 0.1, and 0 and 0.5, respectively (mol/mol
glucose). All byproducts are valuable and may be separated easily by r
ectification of the fermentation broth. Complete cell retention enable
s high volumetric productivity (5 g/Lh), and a minimum of growth suppl
ements. The high temperature of 65 degrees C allows the autoselective
fermentation without problems with contamination.