SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW, NONNATURAL 1-BETA-METHYLCARBAPENEM BEARING A SIGMA-SYMMETRICAL BICYCLOPYRAZOLIUMTHIO GROUP AS THE PENDANT MOIETY

Authors
NAGAO Y TAMAI S TANIGAWA N SANO S KUMAGAI T KISHI I
Citation
Y. Nagao et al., SYNTHESIS AND ANTIBACTERIAL ACTIVITY OF NEW, NONNATURAL 1-BETA-METHYLCARBAPENEM BEARING A SIGMA-SYMMETRICAL BICYCLOPYRAZOLIUMTHIO GROUP AS THE PENDANT MOIETY, Heterocycles, 48(4), 1998, pp. 617-620
Citations number
10
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Heterocycles → ACNP
ISSN journal
03855414
Volume
48
Issue
4
Year of publication
1998
Pages
617 - 620
Database
ISI
SICI code
0385-5414(1998)48:4<617:SAAAON>2.0.ZU;2-B
Abstract
Mercaptobicyclopyrazolium chloride (3) was successfully synthesized st arting from pyrazole (4), and then exploited for the synthesis of new 1 beta-methylcarbapenem (2) which exhibits excellent antibacterial act ivities.