M. Minagawa et A. Tanioka, LEUCINE TRANSPORT THROUGH CATION-EXCHANGE MEMBRANES, EFFECTS OF HCL CONCENTRATION ON INTERFACIAL TRANSPORT, Journal of colloid and interface science, 202(1), 1998, pp. 149-154
The leucine permeability coefficients, P, through a cation exchange me
mbrane were measured as a function of HCl concentration, C-HCl, from 0
to 10(-1) mol/L for three different interfacial conditions and were c
ompared with the results for glycine. Leucine transport phenomena rema
rkably depended on the interfacial condition between the membrane and
the external solution. The lowest P (2.33 x 10(-8) cm(2)/s) was obtain
ed at C-HCl = 0 for both sides of the membrane, and generally P increa
ses with an increase in C-HCl. In case of the glycine, the lowest P (1
.85 x 10(-7) cm(2)/s) had been obtained if C-HCl On the glycine source
side was 10(-1) mol/L and that on the opposite side was 0, The highes
t P (4.34 x 10(-7) cm(2)/s) was obtained if C-HCl On the leucine sourc
e side was 0 and that on the opposite side was 10(-1) mol/L as well as
for glycine (4.16 x 10(-6) cm(2)/s). The P values of glycine had been
explained by the transport mechanism based on the interfacial chemica
l reaction (protonation, deprotonation, or ion-exchange) and the ionic
transport across a charged membrane, The P values of leucine were als
o explained qualitatively by the same mechanism as glycine; however, t
hey are remakably affected by the physicochemical properties of the me
mbrane, such as hydrophobicity and molecular size. (C) 1998 Academic P
ress.