U. Ramakrishnan et R. Martorell, THE ROLE OF VITAMIN-A IN REDUCING CHILD-M ORTALITY AND MORBIDITY AND IMPROVING GROWTH, Salud publica de Mexico, 40(2), 1998, pp. 189-198
This is an update of knowledge on the role of the vitamin A status in
determining child mortality, morbidity and growth. Recent information
confirms the earlier conclusion of Beaten et al. that a 23% reduction
in young child mortality results following improvements in the vitamin
A status. Studies show that the mortality effect is primarily due to
reductions in deaths due to acute gastroenteritis and measles but not
acute respiratory infections (ARI) and malaria. While improvement of t
he vitamin A status enhances the survival of older preschool children,
it remains unclear whether it benefits infants (i.e. <6 months). Vita
min A supplementation does not reduce the overall incidence and preval
ence of common childhood illness; however, it reduces the incidence of
more severe episodes of diarrhea, Also, vitamin A supplementation eit
her during and/or immediately after the illness does not improve its s
ymptomatology. Finally contrary to earlier expectations, recently comp
leted, placebo-controlled randomized interventions have failed to dete
ct improvements in child growth.