PALAUAMINE AND ITS CONGENERS - A FAMILY OF BIOACTIVE BISGUANIDINES FROM THE MARINE SPONGE STYLOTELLA-AURANTIUM

Authors
KINNEL RB GEHRKEN HP SWALI R SKOROPOWSKI G SCHEUER PJ
Citation
Rb. Kinnel et al., PALAUAMINE AND ITS CONGENERS - A FAMILY OF BIOACTIVE BISGUANIDINES FROM THE MARINE SPONGE STYLOTELLA-AURANTIUM, Journal of organic chemistry, 63(10), 1998, pp. 3281-3286
Citations number
39
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of organic chemistry → ACNP
ISSN journal
00223263
Volume
63
Issue
10
Year of publication
1998
Pages
3281 - 3286
Database
ISI
SICI code
0022-3263(1998)63:10<3281:PAIC-A>2.0.ZU;2-P
Abstract
The strongly cytotoxic, antibiotic, and immunosuppressive palau'amine was isolated from the Belau sponge Stylotella aurantium, along with le ss active I-bromo and 4,5-dibromo derivatives. Three corresponding iso meric compounds, all less active, were also isolated, and full details of the isolation and all structure proofs are provided.