EXTRACELLULAR RELEASE OF ANTIGENIC PROTEINS BY HELICOBACTER-PYLORI

Authors
CAO P MCCLAIN MS FORSYTH MH COVER TL
Citation
P. Cao et al., EXTRACELLULAR RELEASE OF ANTIGENIC PROTEINS BY HELICOBACTER-PYLORI, Infection and immunity, 66(6), 1998, pp. 2984-2986
Citations number
26
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
66
Issue
6
Year of publication
1998
Pages
2984 - 2986
Database
ISI
SICI code
0019-9567(1998)66:6<2984:EROAPB>2.0.ZU;2-V
Abstract
Screening a Helicobacter pylori genomic library with antisera raised a gainst H. pylori broth culture supernatant resulted in the identificat ion of six antigens: urease, HspB, Lpp20, DnaK, MsrA, and a cysteine-r ich 28-kDa protein (designated HcpA). H. pylori antigens may be releas ed into the extracellular space by multiple mechanisms, including spec ific secretion pathways, autolysis, and membrane vesicle formation.