IDENTIFICATION AND MOLECULAR ANALYSIS OF LBPBA, WHICH ENCODES THE 2-COMPONENT MENINGOCOCCAL LACTOFERRIN RECEPTOR

Authors
LEWIS LA ROHDE K GIPSON M BEHRENS B GRAY E TOTH SI ROE BA DYER DW
Citation
La. Lewis et al., IDENTIFICATION AND MOLECULAR ANALYSIS OF LBPBA, WHICH ENCODES THE 2-COMPONENT MENINGOCOCCAL LACTOFERRIN RECEPTOR, Infection and immunity, 66(6), 1998, pp. 3017-3023
Citations number
31
Categorie Soggetti
Immunology,"Infectious Diseases
Journal title
Infection and immunity → ACNP
ISSN journal
00199567
Volume
66
Issue
6
Year of publication
1998
Pages
3017 - 3023
Database
ISI
SICI code
0019-9567(1998)66:6<3017:IAMAOL>2.0.ZU;2-1
Abstract
We identified lbpB, encoding the lipoprotein component of the meningoc occal lactoferrin receptor. An LbpB mutant was unable to acquire Fe fr om lactoferrin and exhibits decreased surface binding to lactoferrin. Primer extension and reverse transcription-PCR analysis indicate that lbpB and lbpA are cotranscribed on a polycistronic Fe-repressible mRNA .