A. Pyka, TOPOLOGICAL INDEXES AND R-M VALUES FOR PREDICTION OF THE PK(A) VALUESOF ISOMERIC METHYLANILINES AND CHLOROANILINES - PART-XV, JPC. Journal of planar chromatography, modern TLC, 11(1), 1998, pp. 61-63
Sixteen isomeric methylanilines and chloroanilines have been separated
by TLC on silica gel and on silica gel impregnated with manganese sal
ts and the pK(a) values of the compounds have been correlated with R-M
values and with the numerical values of topological indexes. Most acc
urate prediction of the pK(a) values of the aniline derivatives invest
igated was achieved by use of biparametric equations employing R-M val
ues and the topological indexes degrees B or B-I.