Ac. Ivens et Df. Smith, A GLOBAL MAP OF THE LEISHMANIA-MAJOR GENOME - PRELUDE TO GENOMIC SEQUENCING, Transactions of the Royal Society of Tropical Medicine and Hygiene, 91(2), 1997, pp. 111-115
Citations number
37
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
In 1994, the World Health Organization (TDR) launched a new strategic
initiative in parasite genome analysis, establishing international gen
ome networks for filariae, Schistosoma, Leishmania, Trypanosoma brucei
and T. cruzi. For Leishmania, a number of different but complementary
approaches have been adopted by members of the Leishmania Genome Netw
ork. Our laboratory has been using cosmid clone fingerprinting to prod
uce a physical map of the genome. Progress towards the completion of a
n integrated physical and biological map oft. major and the preparatio
ns for genomic sequencing, are described.