A GLOBAL MAP OF THE LEISHMANIA-MAJOR GENOME - PRELUDE TO GENOMIC SEQUENCING

Authors
IVENS AC SMITH DF
Citation
Ac. Ivens et Df. Smith, A GLOBAL MAP OF THE LEISHMANIA-MAJOR GENOME - PRELUDE TO GENOMIC SEQUENCING, Transactions of the Royal Society of Tropical Medicine and Hygiene, 91(2), 1997, pp. 111-115
Citations number
37
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
Journal title
Transactions of the Royal Society of Tropical Medicine and Hygiene → ACNP
ISSN journal
00359203
Volume
91
Issue
2
Year of publication
1997
Pages
111 - 115
Database
ISI
SICI code
0035-9203(1997)91:2<111:AGMOTL>2.0.ZU;2-B
Abstract
In 1994, the World Health Organization (TDR) launched a new strategic initiative in parasite genome analysis, establishing international gen ome networks for filariae, Schistosoma, Leishmania, Trypanosoma brucei and T. cruzi. For Leishmania, a number of different but complementary approaches have been adopted by members of the Leishmania Genome Netw ork. Our laboratory has been using cosmid clone fingerprinting to prod uce a physical map of the genome. Progress towards the completion of a n integrated physical and biological map oft. major and the preparatio ns for genomic sequencing, are described.