DAILY FLUCTUATION OF LEVELS OF CIRCULATING CATHODIC ANTIGEN IN URINE OF CHILDREN INFECTED WITH SCHISTOSOMA-MANSONI IN BRAZIL

Authors
DISCH J GARCIA MMA KRIJGER GW AMORIM MN KATZ N DEELDER AM GRYSEELS B RABELLO A
Citation
J. Disch et al., DAILY FLUCTUATION OF LEVELS OF CIRCULATING CATHODIC ANTIGEN IN URINE OF CHILDREN INFECTED WITH SCHISTOSOMA-MANSONI IN BRAZIL, Transactions of the Royal Society of Tropical Medicine and Hygiene, 91(2), 1997, pp. 222-225
Citations number
23
Categorie Soggetti
Public, Environmental & Occupation Heath","Tropical Medicine
Journal title
Transactions of the Royal Society of Tropical Medicine and Hygiene → ACNP
ISSN journal
00359203
Volume
91
Issue
2
Year of publication
1997
Pages
222 - 225
Database
ISI
SICI code
0035-9203(1997)91:2<222:DFOLOC>2.0.ZU;2-8
Abstract
The fluctuation of circulating cathodic antigen (CCA) levels in urine was studied in 69 Brazilian schoolchildren infected with Schistosoma m ansoni and compared to egg counts. Faeces and urine samples were simul taneously collected at 7 times during a period of 2 weeks. CCA was det ermined by enzyme-linked immunosorbent assay and could be detected in 96% of the urine samples; the individual mean CCA level ranged from 60 9 to 350 700 pg/mL. 90% of the faecal samples contained S. mansoni egg s and the individual mean egg output ranged from 9 to 5510 eggs/g. The Spearman rank correlation coefficient between these individual means was 0.69. Kendall's coefficient of concordance (W) was 0.88 for CCA le vels and 0.80 for egg counts.