SEROLOGICAL EVIDENCE OF HTLV-I AND HTLV-II COINFECTIONS IN HIV-1 POSITIVE PATIENTS IN BELEM, STATE OF PARA, BRAZIL

The occurrence of HTLV-I/II and HIV-1 coinfections have been shown to be frequently, probably in consequence of their similar modes of trans mission. This paper presents the prevalence of coinfection of HTLV amo ng HIV-1 infected and AIDS patients in Belem, State of Para, Brazil. A group of 149 patients attending the AIDS Reference Unit of the State Department of Health was tested for the presence of antibodies to HTLV -I/II using an enzyme immunoassay and the positive reactions were conf irmed with a Western blot that discriminates between HTLV-I and HTLV-I I infections. Four patients (2.7%) were positive to HTLV-I, seven (4.7 %) to HTLV-II and one (0.7%) showed an indeterminate pattern of reacti on. The present results show for the first time in Belem not only the occurrence of HTLV-II/HIV-1 coinfections but also a higher prevalence of HTLV-II in relation to HTLV-I. Furthermore, it also enlarges the ge ographical limits of the endemic area for HTLV-II in the Amazon region of Brazil.