Ge. Simon et al., IMPACT OF IMPROVED DEPRESSION TREATMENT IN PRIMARY-CARE ON DAILY FUNCTIONING AND DISABILITY, Psychological medicine, 28(3), 1998, pp. 693-701
Background. Few data are available regarding the impact of improved de
pression treatment on daily functioning and disability. Methods. In tw
o studies of more intensive depression treatment in primary care, pati
ents initiating antidepressant treatment were randomly assigned to eit
her usual care or to a collaborative management programme including pa
tient education, on-site mental health treatment, adjustment of antide
pressant medication, behavioural activation and monitoring of medicati
on adherence. Assessments at baseline as well as 4 and 7 months includ
ed several measures of impairment, daily functioning and disability: s
elf-rated overall health, number of bodily pains, number of somatizati
on symptoms, changes in work due to health, reduction in leisure activ
ities due to health, number of disability days and number of restricte
d activity days. Results. Average data from the 4- and 7-month assessm
ents in both studies, intervention patients reported fewer somatic sym
ptoms (OR 0.68, 95% CI 0.46, 0.99) and more favourable overall health
(OR 0.50, 95% CI 0.28, 0.91). While intervention patients fared better
on other measures of functional impairment and disability, none of th
ese differences reached statistical significance. Conclusions. More ef
fective acute-phase depression treatment reduced somatic distress and
improved self-rated overall health. The absence of a significant inter
vention effect on other disability measures may reflect the brief trea
tment and follow-up period and the influence of other individual and e
nvironmental factors on disability.