SYNTHESIS AND CENTRAL-NERVOUS-SYSTEM STIMULANT ACTIVITY OF 5,8-METHANOQUINAZOLINES FUSED WITH 1,2,4-TRIAZOLE, TETRAZOLE AND 1,2,4-TRIAZINE

Authors
NAGAI S UEDA T SUGIURA S NAGATSU A MURAKAMI N SAKAKIBARA J FUJITA M HOTTA Y
Citation
S. Nagai et al., SYNTHESIS AND CENTRAL-NERVOUS-SYSTEM STIMULANT ACTIVITY OF 5,8-METHANOQUINAZOLINES FUSED WITH 1,2,4-TRIAZOLE, TETRAZOLE AND 1,2,4-TRIAZINE, Journal of heterocyclic chemistry, 35(2), 1998, pp. 325-327
Citations number
2
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Journal of heterocyclic chemistry → ACNP
ISSN journal
0022152X
Volume
35
Issue
2
Year of publication
1998
Pages
325 - 327
Database
ISI
SICI code
0022-152X(1998)35:2<325:SACSAO>2.0.ZU;2-G
Abstract
5,8-Methanoquinazolines fused with 1,2,4-triazole 4-5, tetrazole 6, an d 1,2,4-Mazine 8 were prepared starting from 2-hydrazino-5,8-methanoqu inazoline 3. Compound 3 and 6 showed the most potent central nervous s ystem (CNS) stimulant activities.