A STUDY ON ESTER FORMYLHYDRAZONES

A series of ester formylhydrazones 2 were synthesized from the reactio n of alkyl imidate hydrochlorides 1 with formylhydrazine. Treatment of 2 with hydrazine hydrate, ethyl carbazate and tert-butyl carbazate le d to the formation of 3-alkyl-4-amino-, 3-alkyl-4-ethoxycarbonylamino- and lkyl-4-tert-butoxycarbonylamino-4H-1,2,4-triazoles 3-5, respectiv ely. Reaction of compounds 2 with formylhydrazine gave N,N'-diformylhy drazine 6. Compounds 2 were reacted with 2,5-dimethoxytetrahydrofuran to afford 3-alkyl-4-(1H-pyrrol-1-yl)-4H-1,2,4-triazoles 8.