ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES CATALYZED BY A NEW CHIRAL BETA-AMINO ALCOHOL DERIVED FROM D-MANNITOL

Authors
CHO BT CHUN YS
Citation
Bt. Cho et Ys. Chun, ENANTIOSELECTIVE ADDITION OF DIETHYLZINC TO ALDEHYDES CATALYZED BY A NEW CHIRAL BETA-AMINO ALCOHOL DERIVED FROM D-MANNITOL, Tetrahedron : asymmetry, 9(9), 1998, pp. 1489-1492
Citations number
25
Categorie Soggetti
Chemistry Inorganic & Nuclear","Chemistry Inorganic & Nuclear","Chemistry Physical
Journal title
Tetrahedron : asymmetry → ACNP
ISSN journal
09574166
Volume
9
Issue
9
Year of publication
1998
Pages
1489 - 1492
Database
ISI
SICI code
0957-4166(1998)9:9<1489:EAODTA>2.0.ZU;2-K
Abstract
A new chiral beta-dialkylamino alcohol 1 prepared from D-mannitol has been used as a highly effective chiral catalyst for the enantioselecti ve addition of diethylzinc to unhindered aliphatic aldehydes to afford the product alcohols in up to 94% ee. (C) 1998 Elsevier Science Ltd. All rights reserved.