A computer aided monitor-data processing system (CAMP-System) was deve
loped in order to get a consistent and comprehensive database which ca
n very precisely reflect intra-operative haemodynamic courses. The goa
l of the present study was to introduce a new method to scan and to ga
uge haemodynamic courses and to demonstrate its superiority over the t
raditional way oi data processing based on a handwritten anaesthesia p
rotocol. Methods. The computerized system was applied to a study which
was designed to investigate the influence of ketanserin (K) vs. urapi
dil (U) on haemodynamic stability during cardiac operations. Twenty ma
le patients scheduled for myocardial revascularization received either
20 mg K or 30 mg U. Heart rate, central venous, arteria! and pulmonar
y artery pressures were measured and on-line recorded every 20 seconds
by the computer record system. In the handwritten protocol these vari
ables were registered at eight pre-defined time points. Computerized d
ata processing (including artifact depletion and data condensation) wa
s compared to the results evaluated from the handwritten protocol. Res
ults. While the only significant differences in the handwritten protoc
ol were slightly higher values of pulmonary artery pressures in group
K, the computer analysis revealed a number of further differences. Hig
her maximum and a less stable time course of HR in group K in the pre-
bypass phase and lower mean and standard deviation of MAP during cardi
opulmonary bypass. Conclusion. Computerized data processing including
automatic artifact suppression and data condensation was able to revea
l differences in the course of haemodynamic variables that cannot be d
etected in a conventional handwritten protocol.