Mlp. Dirkx et al., LEAF TRAJECTORY CALCULATION FOR DYNAMIC MULTILEAF COLLIMATION TO REALIZE OPTIMIZED FLUENCE PROFILES, Physics in medicine and biology, 43(5), 1998, pp. 1171-1184
An algorithm for the calculation of the required leaf trajectories to
generate optimized intensity modulated beam profiles by means of dynam
ic multileaf collimation is presented. This algorithm iteratively acco
unts for leaf transmission and collimator scatter and fully avoids ton
gue-and-groove underdosage effects. Tests on a large number of intensi
ty modulated fields show that only a limited number of iterations, gen
erally less than 10, are necessary to minimize the differences between
optimized and realized fluence profiles. To assess the accuracy of th
e algorithm in combination with the dose calculation algorithm of the
Cadplan 3D treatment planning system, predicted absolute dose distribu
tions for optimized fluence profiles were compared with dose distribut
ions measured on the MM50 Racetrack Microtron and resulting from the c
alculated leaf trajectories. Both theoretical and clinical cases yield
an agreement within 2%, or within 2 mm in regions with a high dose gr
adient, showing that the accuracy is adequate for clinical application
.