SYNTHESES OF RAC-ACTIVE AND OPTICALLY-ACTIVE 2-ALKYL-GAMMA-BUTYROLACTONES AND 2-ALKYL-CYCLOBUTANONES

Authors
KRIEF A RONVAUX A TUCH A
Citation
A. Krief et al., SYNTHESES OF RAC-ACTIVE AND OPTICALLY-ACTIVE 2-ALKYL-GAMMA-BUTYROLACTONES AND 2-ALKYL-CYCLOBUTANONES, Tetrahedron, 54(24), 1998, pp. 6903-6908
Citations number
13
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
54
Issue
24
Year of publication
1998
Pages
6903 - 6908
Database
ISI
SICI code
0040-4020(1998)54:24<6903:SORAO2>2.0.ZU;2-Q
Abstract
gamma-Butyrolactones have been produced in good yield from alkylidene cyclopropanes, as racemates or as an enantiomerically enriched mixture of stereoisomers (e.e.>60%) depending upon the method used. Optically active cyclobutanones which are intermediate in the process have been in some cases isolated. We show the limitations of a competitive meth od previously described and point out its weak step. (C) 1998 Publishe d by Elsevier Science Ltd. All rights reserved.