MULTIRESISTANT PSEUDOMONAS-AERUGINOSA OUTBREAK ASSOCIATED WITH CONTAMINATED TAP WATER IN A NEUROSURGERY INTENSIVE-CARE UNIT

From July 1995 to November 1996, multi-resistant Pseudomonas aeruginos a O11 was isolated from 36 patients admitted to a neurosurgery intensi ve care unit. The strain was resistant to ticarcillin, ceftazidime, im ipenem, gentamicin and ciprofloxacin, and susceptible to amikacin. Nin e patients were colonized only; the remaining 27 patients had at least one infected site (17 urinary infections, 10 pneumonias and four with sinusitis), P. aeruginosa O11 with the same resistance pattern was is olated from tap water. The strain was also cultured from enteral nutri tion solutions given to two infected patients. DNA macrorestriction an alysis with XbaI established the similarity of the isolates from patie nts, tap water and solutions. The outbreak was controlled after reinfo rcement of isolation procedures for infected patients, changing the mo de of enteral nutrition and replacement of all sinks in the unit. The sinks were presumably the main source of P. aeruginosa during this out break, via the hands of the nursing staff or nutrition solutions conta minated with tap water.