Study Design. Five cases of epidural spinal cavernous hemangioma submi
tted to magnetic resonance imaging and surgery were reviewed. Objectiv
e. To correlate different magnetic resonance imaging appearances of ep
idural spinal cavernous hemangioma with histologic findings. Summary o
f Background Data. Cavernous hemangioma is an uncommon vascular malfor
mation that may occur anywhere in the central nervous system. Purely e
pidural lesions are very rare. Accurate correlation between magnetic r
esonance imaging appearances and histologic findings have not been rep
orted in the literature. Methods. Five cases of epidural spinal cavern
ous hemangioma that had undergone magnetic resonance imaging evaluatio
n followed by microsurgical removal, were retrospectively reviewed. Co
nventional spin-echo T1-, proton density- and T2-weighted magnetic res
onance images were obtained in all cases, and gadolinium was used in a
ll but one. Two cases have also been evaluated with computed tomograph
y. Results. In two cases, magnetic resonance imaging showed mixed low-
and high-signal intensity components in all sequences and pathologic e
xamination showed degenerative phenomena and hemosiderin pigments. In
the remaining three cases, magnetic resonance imaging showed low- or i
ntermediate-signal intensity on T1-weighted and high-signal intensity
on proton density- and T2-weighted images. In those cases, pathologic
examination showed an absence of degenerative phenomena and no signs o
f hemorrhage. All patients underwent surgery by laminectomy and micros
urgical resection. In all, significant improvement was obtained. Concl
usions. Epidural spinal cavernous hemangioma has a different magnetic
resonance imaging appearance probably because of the presence or absen
ce of the degenerative phenomena and hemosiderin pigments. As in cereb
ral locations, mixed signal intensity in all sequences on magnetic res
onance images might be indicative of cavernous hemangioma. Presumptive
preoperative diagnosis of the lesion may render the surgical approach
less invasive.