THE EFFECT OF HIGHLY DILUTED AGITATED THYROXINE ON THE CLIMBING ACTIVITY OF FROGS

We studied the influence of specially prepared highly diluted thyroxin e on the spontaneous tendency of juvenile frogs, which were at the end of thyroxine-controlled metamorphosis, to leave the water and climb o nto land. The test dilution with a thyroxine concentration beyond Avog ardo's value (dilution thyroxine D30) and the reference (dilution wate r D30) were prepared according to directions from the literature on ho meopathy. A few drops of these solutions were added to tap water of ba sins containing the frogs. The frogs' climbing activities were monitor ed immediately after adding the solutions. The hypothesis derived from a preliminary study was that there is less climbing activity in frogs treated with dilution thyroxine D30 than in a reference group. This h ypothesis was proven. Climbing activity diminished under the influence of dilution thyroxine D30, with statistical significance both in comp arison to the effect of the analogously prepared solvent (dilution wat er D30) as well as in comparison to control observations before the st art of treatment. When in a later step of observation the dilution wat er D30-control group was treated with dilution thyroxine D30, the dimi nishing effect on activity also occurred.