PERNICIOUS-ANEMIA IN ASSOCIATION WITH GAS TRIC CARCINOID-TUMORS

Background. - The occurrence of gastric carcinoid tumors during the co re of pernicious anemia has been reported in the literature. Concernin g a new case, we review physiopathological data of this infrequent ass ociation. Case report. - We report the case of a 47-year-old women wit h pernicious anemia in which gastoscopy found two small tumors develop ed from enterochromatoffine-like cells. Conclusion. - These tumors are usually latent and developed from enterochromaffine-like cells. The p athologic and histologic diagnosis is based on positive chromogranin A immunomarking. The physiopathological mechanism studies are in favour of the predominant part of hypergastrinemia following achlorhydria. U sually, evolution is benign and surgical or endoscopic resection recom mended. (C) 1998, Elsevier, Paris.