ISOLATION, IDENTIFICATION, AND ANTIOXIDANT ACTIVITY OF 3 STILBENE GLUCOSIDES NEWLY EXTRACTED FROM VITIS-VINIFERA CELL-CULTURES

Suspension cultures of Vitis vinifera L. (Vitaceae) produce many hydro xylated stilbene glucosides found in red wine. From these cells, we is olated and characterized glycosylated stilbenes, (Z)-piceatannol '-tet rahydroxystilbene)-3-O-beta-D-glucopyranoside (6) and (E)- and (Z)-res veratrol 5,4'-trihydroxystilbene)-4'-O-beta-D-glupyranoside (2 and 7, respectively), which have not previously reported to be constituents o f Vitis vinifera or wine. The ability of these compounds to act as rad ical scavengers was investigated using 1,1 diphenyl-2-picrylhydrazyl, a stable free radical. Antioxidant activities were assessed by their c apacity to prevent Cu2+-induced lipid peroxidation in human low-densit y lipoprotein.