THE HEMATOLOGY ANALYZER SF-3000 - PERFORMANCE OF THE AUTOMATED WHITE BLOOD-CELL DIFFERENTIAL COUNT IN COMPARISON TO THE HEMATOLOGY ANALYZERNE-1500

The present study evaluates the performance of automated white blood c ell (WBC) differential counts by the new Haematology Analyser SF-3000. Five hundred and sixty-six WBC differential counts performed by the S F-3000 were compared with WBC differential counts of the well establis hed analyser NE-1500 and to manual reference counts. Numerical results of the WBC differential counts were correlated to each other by regre ssion analyses. The efficiency of instrument flagging for the presence of abnormal WBC was expressed as per cent of subjects correctly class ified. Neutrophil and lymphocyte counts correlated well between analys ers and to manual reference counts. Monocyte counts for the SF-3000 co rrelated significantly better with the microscopic counts, whereas cor relations of eosinophils and basophils were better for the NE-1500. Th e efficiency rates of nagging for the presence of greater than or equa l to 1% abnormal WBC were 80% for the NE-1500 and 70% for the SF-3000. This difference was exclusively due to low specificity of the SF-3000 in flagging cells of the 'Left Shift' category, especially in samples with elevated WBC counts. The flagging efficiencies for blasts, promy elocytes, myelocytes, atypical lymphocytes and nucleated red cells wer e identical for both analysers. Thus, with regard to the performance o f automated WBC differential counts the SF-3000 seems comparable with other, well established haematology analysers.