TESTOSTERONE INDUCED PRIAPISM IN 2 ADOLESCENTS WITH SICKLE-CELL DISEASE

Citation
W. Slayton et al., TESTOSTERONE INDUCED PRIAPISM IN 2 ADOLESCENTS WITH SICKLE-CELL DISEASE, Journal of pediatric endocrinology & metabolism, 8(3), 1995, pp. 199-203
Citations number
23
Categorie Soggetti
Pediatrics,"Endocrynology & Metabolism
ISSN journal
0334018X
Volume
8
Issue
3
Year of publication
1995
Pages
199 - 203
Database
ISI
SICI code
0334-018X(1995)8:3<199:TIPI2A>2.0.ZU;2-P
Abstract
Priapism is common in pubertal males with sickle cell disease, but the association between lo,v-dose exogenous testosterone administration a nd priapism in such patients has not been well documented. Two adolesc ents with homozygous sickle cell disease (SCD) and delayed maturation with behavioral problems developed priapism about one week after recei ving an intramuscular injection of testosterone enanthate. Neither had a previous history of priapism. We conclude that testosterone should not be administered to male patients with SCD because of the risk of i nducing priapism and possible impotence.