PSEUDOHYPOPARATHYROIDISM TYPE-IA AND GROWTH-HORMONE DEFICIENCY IN 2 SIBLINGS

Authors
SCOTT DC HUNG W
Citation
Dc. Scott et W. Hung, PSEUDOHYPOPARATHYROIDISM TYPE-IA AND GROWTH-HORMONE DEFICIENCY IN 2 SIBLINGS, Journal of pediatric endocrinology & metabolism, 8(3), 1995, pp. 205-207
Citations number
9
Categorie Soggetti
Pediatrics,"Endocrynology & Metabolism
Journal title
Journal of pediatric endocrinology & metabolism → ACNP
ISSN journal
0334018X
Volume
8
Issue
3
Year of publication
1995
Pages
205 - 207
Database
ISI
SICI code
0334-018X(1995)8:3<205:PTAGDI>2.0.ZU;2-C
Abstract
Pseudohypoparathyroidism type Ia (PHP type Ia) is associated with seve ral endocrinopathies, We describe two siblings with PHP type Ia, hypot hyroidism and growth hormone deficiency (GHD). To our knowledge, these patients are the first to have PHP type Ia and GHD. The defect which is most likely responsible for the three endocrinopathies is a deficie ncy of the stimulatory guanine nucleotide-binding regulatory protein, Gs.