TRANSLOCATION (3-13)(Q27-Q14) - A NONRANDOM AND PROBABLY SECONDARY STRUCTURAL-CHANGE IN NON-HODGKIN LYMPHOMAS

Authors
LAI JL DAUDIGNON A KERCKAERT JP GALIEGUEZOUITINA S DETOURMIGNIES L MOREL P BAUTERS F FENAUX P
Citation
Jl. Lai et al., TRANSLOCATION (3-13)(Q27-Q14) - A NONRANDOM AND PROBABLY SECONDARY STRUCTURAL-CHANGE IN NON-HODGKIN LYMPHOMAS, Cancer genetics and cytogenetics, 103(2), 1998, pp. 140-143
Citations number
16
Categorie Soggetti
Oncology,"Genetics & Heredity
Journal title
Cancer genetics and cytogenetics → ACNP
ISSN journal
01654608
Volume
103
Issue
2
Year of publication
1998
Pages
140 - 143
Database
ISI
SICI code
0165-4608(1998)103:2<140:T(-ANA>2.0.ZU;2-8
Abstract
Three cases of (3;13)(q27;q14) translocation observed in different his tological types of non-Hodgkin lymphomas (NHLs) are reported here. Thi s new recurring translocation in NHL was secondary in at least two of the patients because it was associated with another specific change [i .e., t(8;14) (q24;q32) in Burkitt lymphoma and t(14;18)(q32;q21) in ty pical follicular lymphoma]. In two of the cases for which molecular an alysis was performed, a rearrangement of the LAZ-3/BCL-6 gene was foun d. (C) Elsevier Science Inc., 1998.