N. Kurtze et al., THE ROLE OF ANXIETY AND DEPRESSION IN FATIGUE AND PATTERNS OF PAIN AMONG SUBGROUPS OF FIBROMYALGIA PATIENTS, British Journal of Medical Psychology, 71, 1998, pp. 185-194
This study explored the relationship of anxiety and depression with tw
o major symptoms of fibromyalgia, pain and fatigue,among fibromyalgia
patients (N = 322). Due to collinearity between anxiety and depression
scores, extreme groups were defined according to high versus low anxi
ety and depression scores. Two-thirds of the initial sample were exclu
ded by this approach, which permitted a two by two factorial split-plo
t ANOVA for the assessment of main effects and the interaction of anxi
ety and depression upon pain and fatigue. Results stated independent,
additive, effects of anxiety and depression upon levels of pain and fa
tigue, whereas interaction between anxiety and depression failed to si
gnificantly explain symptom differences among the participants. Correl
ational analyses indicated widespread pain among the low anxiety subgr
oups. In contrast, widespread pain was not indicated among anxious pat
ients with low scores on depression. The findings support the hypothes
is that (1) anxiety and depression are independently associated with s
everity of pain symptoms in fibromyalgia, and that (2) patients with h
igh anxiety and low depression may communicate to the medical doctor i
n ways that involve a risk of diagnosing fibromyalgia when the criteri
on of widespread pain is not supported. These conclusions were confirm
ed by results from ANCOVAs that permitted more extensive control of co
llinearity among variables.