There has been a significant increase in the area seeded to minimum-an
d zero-tilled crops worldwide over the past two decades. These croppin
g systems rely primarily on the non-selective herbicides glyphosate or
paraquat/diquat to control weeds before seeding the crop. Both glypho
sate and paraquat/diquat are regarded as low-risk herbicides in the ab
ility of target weeds to develop resistance to them. Following 10-15 y
ears of once annual applications of paraquat and diquat for weed contr
ol in zero-tilled cereals, failure of these herbicides to control Hord
eum glaucum Steud. in two separate fields occurred. Dose-response expe
riments demonstrated high-level resistance to paraquat and diquat in b
oth populations; however, the resistant biotypes are susceptible to ot
her herbicides. This is the first report, worldwide, of paraquat resis
tance following the use of this herbicide in zero-tillage cropping sys
tems and is therefore a harbinger of future problems in minimum-tillag
e systems when there is exclusive reliance on a contact herbicide for
weed control.