USE OF DIPHENYLACETYL CHLORIDE AS PROTECTIVE REAGENT FOR SUGARS

Authors
SANTOYOGONZALEZ F GARCIACALVOFLORES F ISACGARCIA J ROBLESDIAZ R VARGASBERENGUEL A
Citation
F. Santoyogonzalez et al., USE OF DIPHENYLACETYL CHLORIDE AS PROTECTIVE REAGENT FOR SUGARS, Synthesis, (1), 1994, pp. 97-101
Citations number
23
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Synthesis → ACNP
ISSN journal
00397881
Issue
1
Year of publication
1994
Pages
97 - 101
Database
ISI
SICI code
0039-7881(1994):1<97:UODCAP>2.0.ZU;2-K
Abstract
Diphenylacetyl chloride is used as a protective reagent for methyl alp ha-D-glucopyranoside, methyl alpha-D-mannopyranoside, and alpha,alpha- trehalose showing a good regioselectivity. The obtained diphenylacetyl esters were readily removed under neutral and mild conditions with N- bromosuccinimide followed by thiourea, in a one-pot reaction, in the p resence of acetyl or benzoyl groups.