THE SORAPHENS - A FAMILY OF NOVEL ANTIFUNGAL COMPOUNDS FROM SORANGIUM-CELLULOSUM (MYXOBACTERIA) .1. SORAPHEN A(1-ALPHA) - FERMENTATION, ISOLATION, BIOLOGICAL PROPERTIES

Authors
GERTH K BEDORF N IRSCHIK H HOFLE G REICHENBACH H
Citation
K. Gerth et al., THE SORAPHENS - A FAMILY OF NOVEL ANTIFUNGAL COMPOUNDS FROM SORANGIUM-CELLULOSUM (MYXOBACTERIA) .1. SORAPHEN A(1-ALPHA) - FERMENTATION, ISOLATION, BIOLOGICAL PROPERTIES, Journal of antibiotics, 47(1), 1994, pp. 23-31
Citations number
11
Categorie Soggetti
Pharmacology & Pharmacy",Immunology
Journal title
Journal of antibiotics → ACNP
ISSN journal
00218820
Volume
47
Issue
1
Year of publication
1994
Pages
23 - 31
Database
ISI
SICI code
0021-8820(1994)47:1<23:TS-AFO>2.0.ZU;2-9
Abstract
An antifungal activity was detected in the culture broth of Sorangium cellulosum (Myxoccales), strain So ce26. The activity was excreted int o the supernatant during the log and early stationary phase. The activ e substance was quantitatively bound to XAD adsorber resin added to th e medium at the beginning of the fermentation. The new secondary metab olite was called soraphen and is of special interest to plant disease control for its inhibitory activity against numerous phytopathogenic f ungi.