EVALUATION OF THE ANTIBODY-RESPONSE IN PIGS VACCINATED AGAINST STREPTOCOCCUS-SUIS CAPSULAR TYPE-2 USING A DOUBLE-ANTIBODY SANDWICH ENZYME-LINKED-IMMUNOSORBENT-ASSAY

Authors
BLOUIN C HIGGINS R GOTTSCHALK M SIMARD J
Citation
C. Blouin et al., EVALUATION OF THE ANTIBODY-RESPONSE IN PIGS VACCINATED AGAINST STREPTOCOCCUS-SUIS CAPSULAR TYPE-2 USING A DOUBLE-ANTIBODY SANDWICH ENZYME-LINKED-IMMUNOSORBENT-ASSAY, Canadian journal of veterinary research, 58(1), 1994, pp. 49-54
Citations number
34
Categorie Soggetti
Veterinary Sciences
Journal title
Canadian journal of veterinary research → ACNP
ISSN journal
08309000
Volume
58
Issue
1
Year of publication
1994
Pages
49 - 54
Database
ISI
SICI code
0830-9000(1994)58:1<49:EOTAIP>2.0.ZU;2-#
Abstract
A double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) w as standardized for the detection of specific antibodies following vac cination with Streptococcus suis capsular type 2 bacterins. No statist ically significant increase of antibody titers was detected in vaccina ted piglets compared to the nonvaccinated control group, even if a min ority of piglets demonstrated an important postvaccinal response. Thre e of four vaccinated sows showed a low antibody response to vaccine an d specific immunity was detected in piglets of only one litter of thes e three sows. Passive protection studies showed that none of the sera from vaccinated piglets were protective for mice whereas serum obtaine d from hyperimmunized pigs gave protection.