EVALUATION OF THE ANTIBODY-RESPONSE IN PIGS VACCINATED AGAINST STREPTOCOCCUS-SUIS CAPSULAR TYPE-2 USING A DOUBLE-ANTIBODY SANDWICH ENZYME-LINKED-IMMUNOSORBENT-ASSAY
C. Blouin et al., EVALUATION OF THE ANTIBODY-RESPONSE IN PIGS VACCINATED AGAINST STREPTOCOCCUS-SUIS CAPSULAR TYPE-2 USING A DOUBLE-ANTIBODY SANDWICH ENZYME-LINKED-IMMUNOSORBENT-ASSAY, Canadian journal of veterinary research, 58(1), 1994, pp. 49-54
A double-antibody sandwich enzyme-linked immunosorbent assay (ELISA) w
as standardized for the detection of specific antibodies following vac
cination with Streptococcus suis capsular type 2 bacterins. No statist
ically significant increase of antibody titers was detected in vaccina
ted piglets compared to the nonvaccinated control group, even if a min
ority of piglets demonstrated an important postvaccinal response. Thre
e of four vaccinated sows showed a low antibody response to vaccine an
d specific immunity was detected in piglets of only one litter of thes
e three sows. Passive protection studies showed that none of the sera
from vaccinated piglets were protective for mice whereas serum obtaine
d from hyperimmunized pigs gave protection.