Individual differences in emotional reactivity or affective style can
be fruitfully decomposed into more elementary constituents. Several se
parable features of affective style are identified such as the thresho
ld for reactivity, the peak amplitude of response, the rise time to pe
ak and the recovery time. The latter two characteristics constitute co
mponents of affective chronometry. The circuitry that underlies two fu
ndamental forms of motivation and emotion-approach and withdrawal rela
ted processes-is described. Data on individual differences in function
al activity in certain components of these circuits are next reviewed,
with an emphasis on the nomological network of associations surroundi
ng individual differences in asymmetric prefrontal activation. The rel
evance of such differences for understanding the nature of the affecti
ve dysfunction in affective disorders is then considered. The article
ends by considering what the prefrontal cortex ''does'' in certain com
ponents of affective style and highlights some of the important questi
ons for future research.