SYNTHESIS OF NOVEL THIO(SELENO) PHOSPHATE-PHOSPHONATES AND THEIR BIOLOGICAL-ACTIVITIES

In order to search for novel herbicides with high activity and selecti vity, a series of thio(seleno) phosphate-phosphonate derivatives were synthesized in good yields by a one-pot procedure using tris(diethylam ino)phosphine activated by iodine as the phosphorylating reagent. The structures of all compounds prepared were confirmed by spectroscopic m ethods and microanalyses, Preliminary bioassays indicated that some of the products possess potent and selective herbicidal activities and a ntiphytoviral activities against the tobacco mosaic virus (TMV). In ad dition, some of them exhibit significant fungicidal activities against R. Solani and P. Piricola. (C) 1998 John Wiley & Sons, Inc.