Dj. Sexton et al., DUAL INFECTION WITH EHRLICHIA-CHAFFEENSIS AND A SPOTTED-FEVER GROUP RICKETTSIA - A CASE-REPORT, EMERGING INFECTIOUS DISEASES, 4(2), 1998, pp. 311-316
Well-documented cases of simultaneous human infection with more than o
ne tickborne pathogen are rare. To our knowledge only two dual infecti
ons have been reported: simultaneous human infection with the agent of
human granulocytic ehrlichiosis and Borrelia burgdorferi and simultan
eous human infection with B. burgdorferi and Babesia microti (1-2). Ro
cky Mountain spotted fever has long been known to be endemic in North
Carolina; cases of human ehrlichial infection were recognized there so
on after Ehrlichia chaffeensis was recognized as an important cause of
tick-borne disease in the southeastern United States. Because both Ro
cky Mountain spotted fever and ehrlichiosis are prevalent in North Car
olina, occasional cases of simultaneous human infection by rickettsial
and ehrlichial agents would not be surprising; however, no such cases
seem to have been reported.