Nurse hot line calls are a potential source of public health surveilla
nce data and may help identify epidemics of emerging infectious diseas
es. In this study, nurse hot line data from Milwaukee, Wisconsin, show
ed more than a 17-fold increase in calls for diarrhea during the 1993
Milwaukee cryptosporidiosis outbreak. Moreover, consistent patterns of
seasonal variation in diarrhea-and vomiting-related calls were detect
ed from the Baltimore, Maryland, and Albuquerque, New Mexico, hot line
s. Analysis of nurse hot line calls may provide an inexpensive and tim
ely method for improving disease surveillance.